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Coadministration of pexidartinib (a CYP3A4 inducer) with delicate CYP3A substrates could bring about significant therapeutic failures. If concomitant use is unavoidable, boost the CYP3A substrate dosage in accordance with accredited product or service labeling.If coadministration of CYP3A4 inhibitors with fentanyl is necessary, observe patients for